ADARs and the Balance Game between Virus Infection and Innate Immune Cell Response

Abstract excerpt

All viruses that have dsRNA structures at any stages of their life cycle may potentially undergo RNA editing events mediated by the ADAR enzymes. Indeed, an increasing number of studies that describe A-to-I sequence changes in viral genomes and/or transcripts, consistent with ADAR deaminase activity, are reported. These modifications can appear either as hyperediting during persistent viral infections or as...

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