Article

SARS-CoV-2 evasion from ADAR hyper-editing is both genome-encoded and sustained by the virus replication strategy

2021-04-12

Abstract excerpt

<title>Abstract</title> <p>SARS-CoV-2 is threatening the human society because of its capability to subvert antiviral defenses, causing cytokine hyper-activation and prolonged damage in multiple tissues with unpredictable outcomes in the mid-long term. Here, we evaluated the role of ADAR, an interferon-stimulated gene able to control the activation of the immune system and to directly modify exogenous dsRNAs, dur...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 635abdfb-4100-5b2c-9379-15fac30ae289
DOI: 10.21203/rs.3.rs-314516/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 evasion from ADAR hyper-editing is both genome-encoded and sustained by the virus replication strategyDOI 10.21203/rs.3.rs-314516/v2Read

SARS-CoV-2-induced dysregulation in ADAR editing patterns persists post viral clearance in individuals with mild COVID-19Semantic proximity Read

ADAR Editing in Viruses: An Evolutionary Force to Reckon withSemantic proximity Read

Virus-specific editing identification approach reveals the landscape of A-to-I editing and its impacts on SARS-CoV-2 characteristics and evolution.Semantic proximity Read

ADAR mediated A-to-I RNA editing affects SARS-CoV-2 characteristics and fuels its evolutionSemantic proximity Read

Detection of A-to-I RNA Editing in SARS-COV-2Semantic proximity Read

A-to-I RNA editing in SARS-COV-2: real or artifact?Semantic proximity Read

Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2Semantic proximity Read

Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2Semantic proximity Read

SARS-CoV-2 infection induced alterations in ADAR editing patterns differ between patients who developed critical compared to non-critical COVID-19Semantic proximity Read

Reovirus infection induces transcriptome-wide unique A-to-I editing changes in the murine fibroblastsSemantic proximity Read

ADARs and the Balance Game between Virus Infection and Innate Immune Cell ResponseSemantic proximity Read

ADAR1: “Editor-in-Chief” of Cytoplasmic Innate ImmunitySemantic proximity Read