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Article

The DNA virus Invertebrate iridescent virus 6 is a target of the Drosophila RNAi machinery.

Proceedings of the National Academy of Sciences of the United States of America - 18 Dec 2012

Bronkhorst Alfred W, van Cleef Koen W R, Vodovar Nicolas, Ince Ikbal Agah, Blanc Hervé, Vlak Just M, Saleh Maria-Carla, van Rij Ronald P

Abstract excerpt

RNA viruses in insects are targets of an RNA interference (RNAi)-based antiviral immune response, in which viral replication intermediates or viral dsRNA genomes are processed by Dicer-2 (Dcr-2) into viral small interfering RNAs (vsiRNAs). Whether dsDNA virus infections are controlled by the RNAi pathway remains to be determined. Here, we analyzed the role of RNAi in DNA virus infection using Drosophila...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23151511
DOI: 10.1073/pnas.1207213109
PMCID: PMC3529082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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