Article
Preferential expression of cyclooxygenase-2 in colonic-phenotype of gastric intestinal metaplasia: association with helicobacter pylori and gastric carcinoma.
Journal of clinical gastroenterology - 1 Feb 2006
Sun John H, Das Koushik K, Amenta Peter S, Yokota Kinichi, Watari Jiro, Sato Tomonobu, Kohgo Yutaka, Das Kiron M
Abstract excerpt
OBJECTIVES: Gastric intestinal metaplasia (GIM) associated with H. pylori (HP) has been considered a premalignant lesion. However, GIM phenotype associated with HP infection and gastric cancer is unclear. The expression of COX-2 in relation to GIM phenotype is also unknown. METHODS: We evaluated cellular phenotype and COX-2 expression in the GIM from HP-positive and -negative patients from Japan in the absence of...
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