Article
Increased tyrosine kinase activites may lead to the phenotypic differences of gastric cancer cells.
Anticancer research - 1 Jan 2000
Ono Hitoshi, Takeuchi Yoshiaki, Ukegawa Jun-Ichi, Kusayanagi Satoshi, Mitamura Keiji, Imawari Michio
Abstract excerpt
BACKGROUND: The aim of this study was to elucidate possible mechanisms responsible for the phenotypic difference in gastric cancer cells between the intestinal type and the diffuse type. MATERIALS AND METHODS: The gastric cancer cell lines MKN7 and KATO-III were used. Expression of adhesion molecules and protein tyrosine phosphorylation were examined by immunoblotting. Protein-protein interactions were determined...
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