Article
PPARalpha L162V polymorphism alters the potential of n-3 fatty acids to increase lipoprotein lipase activity.
Molecular nutrition & food research - 1 Apr 2010
Rudkowska Iwona, Caron-Dorval Dominique, Verreault Mélanie, Couture Patrick, Deshaies Yves, Barbier Olivier, Vohl Marie-Claude
Abstract excerpt
Omega-3 fatty acids (FAs) may accelerate plasma triglyceride (TG) clearance by altering lipoprotein lipase (LPL) activity. Yet, the ability of n-3 FAs to increase LPL activity is dependent on transcription factors such as peroxisome proliferator-activated receptor alpha (PPARalpha). The objective...
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