Article
The peroxisome proliferator-activated receptor alpha Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men.
The American journal of clinical nutrition - 1 Feb 2005
Paradis Ann-Marie, Fontaine-Bisson Bénédicte, Bossé Yohan, Robitaille Julie, Lemieux Simone, Jacques Hélène, Lamarche Benoît, Tchernof André, Couture Patrick, Vohl Marie-Claude
Abstract excerpt
BACKGROUND: Serum lipid responses to dietary modification are partly determined by genetic factors. OBJECTIVE: We tested whether plasma lipoprotein and lipid responsiveness to a modification in the dietary ratio of polyunsaturated to saturated fatty acids (P:S) is influenced by the peroxisome proliferator-activated receptor alpha (PPARalpha) Leu162Val polymorphism in healthy men. DESIGN: Ten carriers of the V162...
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