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Article

Novel sequence feature variant type analysis of the HLA genetic association in systemic sclerosis.

Human molecular genetics - 15 Feb 2010

Karp David R, Marthandan Nishanth, Marsh Steven G E, Ahn Chul, Arnett Frank C, Deluca David S, Diehl Alexander D, Dunivin Raymond, Eilbeck Karen, Feolo Michael, Guidry Paula A, Helmberg Wolfgang, Lewis Suzanna, Mayes Maureen D, Mungall Chris, Natale Darren A, Peters Bjoern, Petersdorf Effie, Reveille John D, Smith Barry, Thomson Glenys, Waller Matthew J, Scheuermann Richard H

Abstract excerpt

We describe a novel approach to genetic association analyses with proteins sub-divided into biologically relevant smaller sequence features (SFs), and their variant types (VTs). SFVT analyses are particularly informative for study of highly polymorphic proteins such as the human leukocyte antigen...

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Source

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Identifiers

PMID: 19933168
DOI: 10.1093/hmg/ddp521
PMCID: PMC2807365

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19933168-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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