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Next-Generation Sequencing Based HLA Typing: Deciphering Immunogenetic Aspects of Sarcoidosis

25 Oct 2018

Abstract excerpt

Unraveling of the HLA-related immunogenetic basis of several immune disorders is complex due to the extensive HLA polymorphism and strong linkage-disequilibrium between HLA loci. A lack of in phase sequence information, a relative deficiency of high resolution genotyping including non-coding regions and ambiguous haplotype assignment make it difficult to compare findings across association studies and to...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 30410504
DOI: 10.3389/fgene.2018.00503

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