Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MafB protein stability is regulated by the JNK and ubiquitin-proteasome pathways.

Archives of biochemistry and biophysics - 1 Feb 2010

Tanahashi Hiroshi, Kito Keiji, Ito Takashi, Yoshioka Katsuji

Abstract excerpt

MafB is a basic leucine zipper transcription factor that plays important roles in development and differentiation processes. During osteoclastogenesis, its expression is downregulated at the transcriptional level via the JNK and p38 MAP kinase pathways. In the present study, we demonstrated that MafB protein stability is regulated by JNK and identified a phosphorylation site, Thr62. The expression of a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to COS Cells
Share to Enzyme Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoprecipitation

Share to MafB Transcription Factor

Share to MAP Kinase Kinase 4

Share to Proteasome Endopeptidase Complex

Share to Ubiquitin

Source

Identifiers

PMID: 19932079
DOI: 10.1016/j.abb.2009.11.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MafB protein stability is regulated by the JNK and ubiquitin-proteasome pathways.PMID 19932079Read ↗

JUNB‐FBXO21‐ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagySemantic proximity Read ↗

MafA transcription factor is phosphorylated by p38 MAP kinase.Semantic proximity Read ↗

Role of MafB in macrophagesSemantic proximity Read ↗

Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell ProliferationSemantic proximity Read ↗

JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.Semantic proximity Read ↗

Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination.Semantic proximity Read ↗

SUMOylation negatively regulates transcriptional and oncogenic activities of MafA.Semantic proximity Read ↗

IkappaB kinase beta promotes cell survival by antagonizing p53 functions through DeltaNp73alpha phosphorylation and stabilization.Semantic proximity Read ↗

Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation.Semantic proximity Read ↗

The stability and transactivation potential of the mammalian MafA transcription factor are regulated by serine 65 phosphorylation.Semantic proximity Read ↗

Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins.Semantic proximity Read ↗

MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.