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Article

Zyxin controls migration in epithelial-mesenchymal transition by mediating actin-membrane linkages at cell-cell junctions.

Journal of cellular physiology - 1 Mar 2010

Sperry Rebecca Bakkevig, Bishop Nicholas H, Bramwell Jeremy J, Brodeur Michael N, Carter Matthew J, Fowler Brent T, Lewis Zachery B, Maxfield Steve D, Staley Davis M, Vellinga Ryan M, Hansen Marc D H

Abstract excerpt

Development is punctuated by morphogenetic rearrangements of epithelial tissues, including detachment of motile cells during epithelial-mesenchymal transition (EMT). Dramatic actin rearrangements occur as cell-cell junctions are dismantled and cells become independently motile during EMT. Characterizing dynamic actin rearrangements and identifying actin machinery driving these rearrangements is essential for...

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Source

Identifiers

PMID: 19927303
DOI: 10.1002/jcp.21977

Genes

VASP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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