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Article

Nuclear Actin Polymerization Regulates Cell Epithelial‐Mesenchymal Transition

11 Aug 2023

Abstract excerpt

Current studies on actin function primarily rely on cytoplasmic actin due to the absence of cellular models specifically expressing nuclear actin. Here, cell models capable of expressing varying levels of nuclear F/G-actin are generated and a significant role of nuclear actin in the regulation of epithelial-mesenchymal transition (EMT) is uncovered. Through immunoprecipitation and mass spectrometry analyses,...

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PMID: 37566765
DOI: 10.1002/advs.202300425

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