Article
Myosin X regulates sealing zone patterning in osteoclasts through linkage of podosomes and microtubules.
The Journal of biological chemistry - 26 Mar 2010
McMichael Brooke K, Cheney Richard E, Lee Beth S
Abstract excerpt
Osteoclasts use actin-rich attachment structures in place of focal adhesions for adherence to bone and non-bone substrates. On glass, osteoclasts generate podosomes, foot-like processes containing a core of F-actin and regulatory proteins that undergo high turnover. To facilitate bone resorption,...
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