Article

Vglut2 expression in dopamine neurons contributes to post-lesional striatal reinnervation

2019-12-24

Abstract excerpt

<h4>ABSTRACT</h4> In Parkinson’s disease, the most vulnerable neurons are found in the ventral tier of the substantia nigra (SN), while the adjacent dopamine (DA) neurons of the ventral tegmental area (VTA) are mostly spared. Although a significant subset of adult VTA DA neurons expresses Vglut2 , a vesicular glutamate transporter, and release glutamate as a second neurotransmitter in the striatum, only very few...

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Literature Corpus work: 29ae60af-1967-555a-953e-d047a772e1f2
DOI: 10.1101/2019.12.23.887323

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