Article
Polymorphisms of the apoptosis-associated gene DP1L1 (deleted in polyposis 1-like 1) in colon cancer and inflammatory bowel disease.
Journal of cancer research and clinical oncology - 1 Jun 2010
Wellmann Axel, Fogt Franz, Hollerbach Stephan, Hahne Jens, Koenig-Hoffmann Kerstin, Smeets Daniela, Brinkmann Ulrich
Abstract excerpt
PURPOSE: The deleted-in-polyposis1-like1 (DP1L1) gene displays pro-apoptotic activity and was proposed to be a tumor suppressor. It locates on chromosome 19p13.3, which harbors the locus for Peutz-Jeghers-Syndrome and is deleted in various tumors. We analyzed the association of DP1L1 polymorphism...
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