Article
A novel gene containing PDZ and LIM domains, PCD1, is overexpressed in human colorectal cancer.
Anticancer research - 1 Jan 2000
Furuya Momoko, Tsuji Naoki, Endoh Teruo, Moriai Ryosuke, Kobayashi Daisuke, Yagihashi Atsuhito, Watanabe Naoki
Abstract excerpt
BACKGROUND: The process of colorectal cancer development involves accumulated genetic alterations affecting APC, K-ras and p53. A recently identified gene, PCD1, was reported to be up-regulated in human malignancies including colorectal cancers, but relationships between PCD1 gene expression and clinicopathological findings, as well as the timing of genetic alteration of PCD1 in colorectal cancer development, are...
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