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Article

Profiling critical cancer gene mutations in clinical tumor samples.

PloS one - 18 Nov 2009

MacConaill Laura E, Campbell Catarina D, Kehoe Sarah M, Bass Adam J, Hatton Charles, Niu Lili, Davis Matt, Yao Keluo, Hanna Megan, Mondal Chandrani, Luongo Lauren, Emery Caroline M, Baker Alissa C, Philips Juliet, Goff Deborah J, Fiorentino Michelangelo, Rubin Mark A, Polyak Kornelia, Chan Jennifer, Wang Yuexiang, Fletcher Jonathan A, Santagata Sandro, Corso Gianni, Roviello Franco, Shivdasani Ramesh, Kieran Mark W, Ligon Keith L, Stiles Charles D, Hahn William C, Meyerson Matthew L, Garraway Levi A

Abstract excerpt

BACKGROUND: Detection of critical cancer gene mutations in clinical tumor specimens may predict patient outcomes and inform treatment options; however, high-throughput mutation profiling remains underdeveloped as a diagnostic approach. We report the implementation of a genotyping and validation a...

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Identifiers

PMID: 19924296
DOI: 10.1371/journal.pone.0007887
PMCID: PMC2774511

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19924296-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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