Article
An institutional review of genomic sequencing in pediatric solid tumors.
Pediatric blood & cancer - 1 Jun 2023
Turco George M, Gupta Ajay, Monteleone Philip, Kelly Kara M, Klein Roger D, Wiltsie Laura, Barth Matthew
Abstract excerpt
BACKGROUND: Although tumor genomic profiling has aided the advancement of targeted genetic therapy, its clinical integration remains a challenge in pediatric cancers due to lower mutation frequency and less available targeted drugs. There have been multiple novel studies examining molecular sequencing in pediatrics; however, many of these studies primarily utilized large-scale, genome-wide screening applications...
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