Article
The heterogeneous allelic repertoire of human toll-like receptor (TLR) genes.
PloS one - 17 Nov 2009
Georgel Philippe, Macquin Cécile, Bahram Seiamak
Abstract excerpt
Toll-Like Receptors (TLR) are critical elements of the innate arm of the vertebrate immune system. They constitute a multigenic family of receptors which collectively bind a diverse array of--exogeneous as well as endogeneous--ligands. An exponential burst of knowledge has defined their biological role in fight against infections and generation/modulation of auto-immune disorders. Hence, they could at least be...
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