Article
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells.
Molecular and cellular biology - 1 Sept 2002
Itoh Reina E, Kurokawa Kazuo, Ohba Yusuke, Yoshizaki Hisayoshi, Mochizuki Naoki, Matsuda Michiyuki
Abstract excerpt
Rho family G proteins, including Rac and Cdc42, regulate a variety of cellular functions such as morphology, motility, and gene expression. We developed fluorescent resonance energy transfer-based probes which monitored the local balance between the activities of guanine nucleotide exchange facto...
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