Article
Diverging effects of HLA-DPB1 matching status on outcome following unrelated donor transplantation depending on disease stage and the degree of matching for other HLA alleles.
Leukemia - 1 Jan 2010
Shaw B E, Mayor N P, Russell N H, Apperley J F, Clark R E, Cornish J, Darbyshire P, Ethell M E, Goldman J M, Little A-M, Mackinnon S, Marks D I, Pagliuca A, Thomson K, Marsh S G E, Madrigal J A
Abstract excerpt
Disease stage and recipient/donor human leukocyte antigen (HLA) matching are important determinants of outcome in transplantation using volunteer-unrelated donors (VUD). Matching for HLA-A, -B, -C, -DRB1, -DQB1 is beneficial, whereas the importance of DPB1 matching is more controversial. The impact of HLA matching status may differ dependent on disease stage. We investigated the outcome according to the degree of...
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