Article
Immunogenetic factors in donors and patients that affect the outcome of hematopoietic stem cell transplantation.
Blood cells, molecules & diseases - 1 Jan 2000
Madrigal Alejandro, Shaw Bronwen E
Abstract excerpt
We have correlated the clinical outcome with the level of HLA matching in 423 patients who received a transplant from a volunteer unrelated donor in the United Kingdom. HLA matching was performed at the allelic level (i.e. high-resolution) using reference strand mediated conformation analysis (RSCA) at HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1. The three-year probability of overall survival (OS) was 45% (median...
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