Article
Involvement of mitochondrial DNA sequence variations and respiratory activity in late complications following radiotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2009
Alsbeih Ghazi A, Al-Harbi Najla M, El-Sebaie Medhat M, Al-Rajhi Nasser M, Al-Hadyan Khaled S, Abu-Amero Khaled K
Abstract excerpt
PURPOSE: Mitochondria and ionizing radiation overlap in a number of features; for instance, both generate harmful reactive oxygen species, and that radiation can induce cell death through the intermediary of mitochondria. Because a number of genetic variations in nuclear genes are frequently asso...
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