Genetic variants and normal tissue toxicity after radiotherapy: a systematic review.

doi:10.1016/j.radonc.2009.06.015

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Article

Genetic variants and normal tissue toxicity after radiotherapy: a systematic review.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Sept 2009

Andreassen Christian Nicolaj, Alsner Jan

Abstract excerpt

During the last decade, nearly 60 studies have addressed possible associations between various genetic sequence alterations and risk of adverse reactions after radiotherapy. We report here an overview of these studies with information on the genetic variants, tumour type, number of patients included, the endpoint studied, the mechanism(s) by which the candidate genes are involved in the pathogenesis of normal...

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Identifiers

PMID: 19683821
DOI: 10.1016/j.radonc.2009.06.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.