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Gene Expression Profiles Classify Human Osteosarcoma Xenografts According to Sensitivity to Doxorubicin, Cisplatin, and Ifosfamide

17 Nov 2009

Abstract excerpt

PURPOSE: In osteosarcoma, aggressive preoperative and postoperative multidrug chemotherapy given to all patients has improved patient survival rate to the present level of approximately 60%. However, no tumor marker is available that reliably can identify those patients who will or will not respond to chemotherapy. EXPERIMENTAL DESIGN: In an attempt to find leads to such markers, we have obtained microarray gene...

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PMID: 19920113
DOI: 10.1158/1078-0432.ccr-08-2816

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