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Article

Gene Expression Profile Associated with Response to Doxorubicin-Based Therapy in Breast Cancer

15 Oct 2005

Abstract excerpt

PURPOSE: This study was designed to identify genes that could predict response to doxorubicin-based primary chemotherapy in breast cancer patients. EXPERIMENTAL DESIGN: Biopsy samples were obtained before primary treatment with doxorubicin and cyclophosphamide. RNA was extracted and amplified and gene expression was analyzed using cDNA microarrays. RESULTS: Response to chemotherapy was evaluated in 51 patients,...

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PMID: 16243817
DOI: 10.1158/1078-0432.ccr-04-0548

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