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Article

Individualized chemotherapy for osteosarcoma and identification of gene mutations in osteosarcoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2015

Xiao Xin, Wang Wei, Zhang Haoqiang, Gao Peng, Fan Bo, Huang Chen, Fu Jun, Chen Guojing, Shi Lei, Zhu Haodong, Li Xiangdong, Li Jing, Fan Hongbin, Wu Zhigang, Guo Zheng, Hu Yongcheng, Wu Sujia, Yu Xiuchun, Xu Cheng, Wang Zhen

Abstract excerpt

The study aims to identify novel gene mutations in osteosarcoma and to guide individualized preoperative chemotherapy for osteosarcoma based on the analysis of expression and mutations of the drug-metabolism-related genes. Twenty-eight osteosarcoma patients received individualized preoperative chemotherapy regimens. Expression levels and mutations of chemotherapy-related genes in samples collected from the...

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PMID: 25431261
DOI: 10.1007/s13277-014-2853-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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