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Article

α1-Adrenergic Receptor Subtypes in Nonfailing and Failing Human Myocardium

7 Aug 2009

Abstract excerpt

BACKGROUND: alpha1-adrenergic receptors (alpha1-ARs) play adaptive roles in the heart and protect against the development of heart failure. The 3 alpha1-AR subtypes, alpha1A, alpha1B, and alpha1D, have distinct physiological roles in mouse heart, but very little is known about alpha1 subtypes in human heart. Here, we test the hypothesis that the alpha1A and alpha1B subtypes are present in human myocardium,...

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PMID: 19919991
DOI: 10.1161/circheartfailure.108.846212

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