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Article

Selection-driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection.

Hepatology (Baltimore, Md.) - 1 Feb 2010

Fuller Michael J, Shoukry Naglaa H, Gushima Toshifumi, Bowen David G, Callendret Benoit, Campbell Katherine J, Hasselschwert Dana L, Hughes Austin L, Walker Christopher M

Abstract excerpt

UNLABELLED: Immune escape driven by selection pressure from virus-specific CD8 T cells has been demonstrated in both chimpanzees and humans infected with the hepatitis C virus (HCV). Although escape mutations have also been characterized in major histocompatibility complex (MHC) class II-restricted HCV epitopes, it is unknown whether selection-driven immune escape by CD4 T cell epitopes is a significant factor in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19918975
DOI: 10.1002/hep.23319
PMCID: PMC2821874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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