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Article

Evaluation of a shared autoimmune disease-associated polymorphism of TRAF6 in systemic sclerosis and giant cell arteritis.

The Journal of rheumatology - 1 Jun 2012

Carmona F David, Serrano Aurora, Rodríguez-Rodríguez Luis, Callejas José Luis, Simeón Carmen P, Carreira Patricia, Castañeda Santos, Solans Roser, Blanco Ricardo, González-Gay Miguel A, Martín Javier

Abstract excerpt

OBJECTIVE: We evaluated whether a single-nucleotide polymorphism (SNP) of the TRAF6 gene previously associated with systemic lupus erythematosus and rheumatoid arthritis may be a common risk factor for systemic sclerosis (SSc) and giant cell arteritis (GCA). METHODS: A total of 1185 patients with SSc, 479 patients with biopsy-proven GCA, and 1442 unrelated healthy controls of white Spanish origin were genotyped...

Read the complete abstract on PubMed

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Share to Autoimmune Diseases
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Giant Cell Arteritis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to TNF Receptor-Associated Factor 6

Source

Identifiers

PMID: 22589256
DOI: 10.3899/jrheum.120038

Genes

GCA
TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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