Article
The zinc-responsive regulator Zur controls expression of the coelibactin gene cluster in Streptomyces coelicolor.
Journal of bacteriology - 1 Jan 2010
Kallifidas Dimitris, Pascoe Ben, Owen Gillian A, Strain-Damerell Claire M, Hong Hee-Jeon, Paget Mark S B
Abstract excerpt
Streptomyces coelicolor mutants lacking the zinc-responsive Zur repressor are conditionally defective in sporulation, presumably due to the overexpression of one or more Zur target genes. Gene disruption analyses revealed that deregulation of previously known Zur targets was not responsible for the sporulation phenotype. We used microarrays to identify further Zur targets and discovered that Zur controls a...
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