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Article

Genomewide insertional mutagenesis in Streptomyces coelicolor reveals additional genes involved in morphological differentiation.

Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 2000

Gehring A M, Nodwell J R, Beverley S M, Losick R

Abstract excerpt

The filamentous soil bacterium Streptomyces coelicolor undergoes a complex cycle of morphological differentiation involving the formation of an aerial mycelium and the production of pigmented antibiotics. We have developed a procedure for generating insertional mutants of S. coelicolor based on in vitro transposition of a plasmid library of cloned S. coelicolor DNAs. The insertionally mutated library was...

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Identifiers

PMID: 10931952
DOI: 10.1073/pnas.170059797
PMCID: PMC16918

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Source receipt: pubmed, retrieved 7 Sept 2026.

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