Article
Novel genes that influence development in Streptomyces coelicolor.
Journal of bacteriology - 1 Jun 2004
Gehring Amy M, Wang Stephanie T, Kearns Daniel B, Storer Narie Yoo, Losick Richard
Abstract excerpt
Filamentous soil bacteria of the genus Streptomyces carry out complex developmental cycles that result in sporulation and production of numerous secondary metabolites with pharmaceutically important activities. To further characterize the molecular basis of these developmental events, we screened for mutants of Streptomyces coelicolor that exhibit aberrant morphological differentiation and/or secondary metabolite...
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