Article
Characterization of Zur-dependent genes and direct Zur targets in Yersinia pestis.
BMC microbiology - 25 Jun 2009
Li Yingli, Qiu Yefeng, Gao He, Guo Zhaobiao, Han Yanping, Song Yajun, Du Zongmin, Wang Xiaoyi, Zhou Dongsheng, Yang Ruifu
Abstract excerpt
BACKGROUND: The zinc uptake regulator Zur is a Zn2+-sensing metalloregulatory protein involved in the maintenance of bacterial zinc homeostasis. Up to now, regulation of zinc homeostasis by Zur is poorly understood in Y. pestis. RESULTS: We constructed a zur null mutant of Y. pestis biovar microtus strain 201. Microarray expression analysis disclosed a set of 154 Zur-dependent genes of Y. pestis upon exposure to...
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