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Article

Early and sustained altered expression of aging-related genes in young 3xTg-AD mice.

Cell death & disease - 13 Feb 2014

Gatta V, D'Aurora M, Granzotto A, Stuppia L, Sensi S L

Abstract excerpt

Alzheimer's disease (AD) is a multifactorial neurological condition associated with a genetic profile that is still not completely understood. In this study, using a whole gene microarray approach, we investigated age-dependent gene expression profile changes occurring in the hippocampus of young and old transgenic AD (3xTg-AD) and wild-type (WT) mice. The aim of the study was to assess similarities between...

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Identifiers

PMID: 24525730
DOI: 10.1038/cddis.2014.11
PMCID: PMC3944230

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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