Article
akirin is required for diakinesis bivalent structure and synaptonemal complex disassembly at meiotic prophase I.
Molecular biology of the cell - 1 Apr 2013
Clemons Amy M, Brockway Heather M, Yin Yizhi, Kasinathan Bhavatharini, Butterfield Yaron S, Jones Steven J M, Colaiácovo Monica P, Smolikove Sarit
Abstract excerpt
During meiosis, evolutionarily conserved mechanisms regulate chromosome remodeling, leading to the formation of a tight bivalent structure. This bivalent, a linked pair of homologous chromosomes, is essential for proper chromosome segregation in meiosis. The formation of a tight bivalent involves chromosome condensation and restructuring around the crossover. The synaptonemal complex (SC), which mediates...
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