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Article

The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.

Nature communications - 26 May 2021

Chen Yanyan, Wang Yan, Chen Juan, Zuo Wu, Fan Yong, Huang Sijia, Liu Yongmei, Chen Guangming, Li Qing, Li Jinsong, Wu Jian, Bian Qian, Huang Chenhui, Lei Ming

Abstract excerpt

Chromosomes pair and synapse with their homologous partners to segregate correctly at the first meiotic division. Association of telomeres with the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex composed of SUN1 and KASH5 enables telomere-led chromosome movements and telomere bouquet formation, facilitating precise pairwise alignment of homologs. Here, we identify a direct interaction between SUN1 and...

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Identifiers

PMID: 34039995
DOI: 10.1038/s41467-021-23550-w
PMCID: PMC8155084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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