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Article

Identification of polymorphisms in genes of the immune system in cynomolgus macaques.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2012

Wu Hong, Adkins Karissa

Abstract excerpt

Cynomolgus macaques are a standard species used preclinically for evaluating efficacy and toxicity of therapeutic drug candidates and vaccines. However, findings from preclinical studies conducted in cynomolgus macaques are often highly variable, which may in part be attributed to genetic diversity. In this study, genetic polymorphisms were identified in 49 genes of the immune system using DNA isolated from 40...

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PMID: 22527486
DOI: 10.1007/s00335-012-9399-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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