Article
Mitochondrial respiratory dysfunction and mutations in mitochondrial DNA in PINK1 familial parkinsonism.
Journal of bioenergetics and biomembranes - 1 Dec 2009
Papa Sergio, Sardanelli Anna Maria, Capitanio Nazzareno, Piccoli Claudia
Abstract excerpt
A summary is presented of the cellular function and topology of the protein products of genes whose mutations are associated with familial forms of parkinsonism, with particular emphasis on mitochondrial involvement. Observations are reviewed which show mitochondrial respiratory depression in the...
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