Article
Novel mitochondrial DNA mutations in Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) - 1 May 2002
Richter G, Sonnenschein A, Grünewald T, Reichmann H, Janetzky B
Abstract excerpt
Despite the recent discovery of several chromosomal gene mutations in familial Parkinson's disease (PD) the genetic background for idiopathic PD remains to be elusive. Since the discovery of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) action on dopaminergic neuronal cells and the specific...
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