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Article

PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases.

Oncotarget - 4 Apr 2017

Ziv Etay, Bergen Michael, Yarmohammadi Hooman, Boas F Ed, Petre E Nadia, Sofocleous Constantinos T, Yaeger Rona, Solit David B, Solomon Stephen B, Erinjeri Joseph P

Abstract excerpt

PURPOSE: To establish the relationship between common mutations in the MAPK and PI3K signaling pathways and local progression after radioembolization. MATERIALS AND METHODS: Retrospective review of a HIPAA-compliant institutional review-board approved database identified 40 patients with chemo-refractory colorectal liver metastases treated with radioembolization who underwent tumor genotyping for hotspot...

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Share to Colorectal Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Multivariate Analysis

Share to Outcome Assessment, Health Care

Share to Phosphatidylinositol 3-Kinases

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Source

Open in PubMed Open full text

Identifiers

PMID: 28206962
DOI: 10.18632/oncotarget.15278
PMCID: PMC5410324

Genes

AKT1
BRAF
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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