Article
The proline-rich domain of tau plays a role in interactions with actin.
BMC cell biology - 8 Nov 2009
He Hai Jin, Wang Xing Sheng, Pan Rong, Wang Dong Liang, Liu Ming Nan, He Rong Qiao
Abstract excerpt
BACKGROUND: The microtubule-associated protein tau is able to interact with actin and serves as a cross-linker between the microtubule and actin networks. The microtubule-binding domain of tau is known to be involved in its interaction with actin. Here, we address the question of whether the other domains of tau also interact with actin. RESULTS: Several tau truncation and deletion mutants were constructed,...
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