Heterogeneous Tau-Tubulin Complexes Accelerate Microtubule Polymerization.

Abstract excerpt

Tau is an intrinsically disordered protein with a central role in the pathology of a number of neurodegenerative diseases. Tau normally functions to stabilize neuronal microtubules, although the mechanism underlying this function is not well understood. Of note is that the interaction between tau and soluble tubulin, which has implications both in understanding tau function as well as its role in disease, is...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Brain
• Share to Cattle
• Share to Diffusion