Article
Viral genetic determinants of nonprogressive HIV type 1 subtype C infection in antiretroviral drug-naive children.
AIDS research and human retroviruses - 1 Nov 2009
Tzitzivacos D B, Tiemessen C T, Stevens W S, Papathanasopoulos M A
Abstract excerpt
Characterization of HIV-1 from slow progressors is important to facilitate vaccine and antiviral drug development. To identify virus attenuations that may contribute to slower rates of disease progression, the full-length viral genomes from primary isolates of six slow progressing HIV-positive children were sequenced. Proviral DNA was extracted from cocultured peripheral blood mononuclear cells and used to PCR...
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