Article
Genetic and functional characterization of human immunodeficiency virus type 1 VprC variants from north India: presence of unique recombinants with mosaic genomes from B, C and D subtypes within the open reading frame of Vpr.
The Journal of general virology - 1 Nov 2009
Bano Aalia S, Sood Vikas, Neogi Ujjwal, Goel Nidhi, Kuttiat Vijesh Sreedhar, Wanchu Ajay, Banerjea Akhil C
Abstract excerpt
The human immunodeficiency virus type 1 (HIV-1) epidemic in India is predominantly caused by genetic subtype C, though other minor subtypes have also been reported. One of the major accessory proteins of HIV-1, namely Vpr, is known to influence key steps in viral replication, cell cycle progression, promoter activation, apoptosis and pathogenesis. Therefore, we carried out a genetic and functional analysis of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.