Article
Molecular Characterization of the pol Gene of Vertically Transmitted HIV-1 Strains in Children with Virological Failure.
AIDS research and human retroviruses - 1 Jun 2022
Karunaianantham Ramesh, Nesa Kumar Manohar, Gopalan Bindu, Haribabu Hemalatha, Hanna Luke Elizabeth, Sanjeeva G N, Reddy Devarajulu, Shet Anita, Swaminathan Soumya, Padmapriyadarsini Chandrasekaran
Abstract excerpt
HIV-1 pol gene sequences were analyzed from 77 HIV-1 positive children infected perinatally and exhibiting virological failure (VF). Viral subtyping, phylogenetic analysis, and genotypic drug resistance analysis were carried out on samples collected before start of anti retroviral treatment (ART)...
Topics
- Anti-HIV Agents
- Child
- Drug Resistance, Viral
- Genes, pol
- Genotype
- HIV Infections
- HIV Seropositivity
- HIV-1
- Humans
- Infectious Disease Transmission, Vertical
- Mutation
- Phylogeny
- Pyridazines
- Reverse Transcriptase Inhibitors