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Article

The rad52-Y66A allele alters the choice of donor template during spontaneous chromosomal recombination.

DNA repair - 2 Jan 2010

de Mayolo Adriana Antúnez, Sunjevaric Ivana, Reid Robert, Mortensen Uffe H, Rothstein Rodney, Lisby Michael

Abstract excerpt

Spontaneous mitotic recombination is a potential source of genetic changes such as loss of heterozygosity and chromosome translocations, which may lead to genetic disease. In this study we have used a rad52 hyper-recombination mutant, rad52-Y66A, to investigate the process of spontaneous heteroallelic recombination in the yeast Saccharomyces cerevisiae. We find that spontaneous recombination has different genetic...

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Source

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Identifiers

PMID: 19892607
DOI: 10.1016/j.dnarep.2009.10.001
PMCID: PMC2818265

Genes

MRE11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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