Article
The role of recombination and RAD52 in mutation of chromosomal DNA transformed into yeast.
Nucleic acids research - 11 Oct 1994
Larionov V, Graves J, Kouprina N, Resnick M A
Abstract excerpt
While transformation is a prominent tool for genetic analysis and genome manipulation in many organisms, transforming DNA has often been found to be unstable relative to established molecules. We determined the potential for transformation-associated mutations in a 360 kb yeast chromosome III com...
Topics
- Chromosomes, Fungal
- Culture Media
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Galactose
- Gene Deletion
- Mutation
- Rad52 DNA Repair and Recombination Protein
- Recombination, Genetic
- Saccharomyces
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transformation, Genetic