Article
The role of recombination and RAD52 in mutation of chromosomal DNA transformed into yeast.
Nucleic acids research - 11 Oct 1994
Larionov V, Graves J, Kouprina N, Resnick M A
Abstract excerpt
While transformation is a prominent tool for genetic analysis and genome manipulation in many organisms, transforming DNA has often been found to be unstable relative to established molecules. We determined the potential for transformation-associated mutations in a 360 kb yeast chromosome III composed primarily of unique DNA. Wild-type and rad52 Saccharomyces cerevisiae strains were transformed with either a...
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