Article
Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast.
Current genetics - 1 Jan 1995
Montelone B A, Koelliker K J
Abstract excerpt
The mutant alleles mms9-1, mms13-1, or mms21-1 of Saccharomyces cerevisiae confer pleiotropic effects, including sensitivity to the alkylating agent methyl methanesulfonate, elevations in spontaneous mutation and mitotic recombination, defects in meiosis, and cross-sensitivity to radiation. We constructed double-mutant strains containing an mms mutation and a defect in either excision repair, mutagenic repair, or...
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