Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selection of escape mutation by Pol154-162-specific cytotoxic T cells among chronically HIV-1-infected HLA-B*5401-positive individuals.

Human immunology - 1 Feb 2010

Hashimoto Masao, Kitano Mitsutaka, Honda Kazutaka, Koizumi Hirokazu, Dohki Sachi, Oka Shinichi, Takiguchi Masafumi

Abstract excerpt

Most escape mutations have been identified on cytotoxic T lymphocyte (CTL) epitopes presented by Caucasian or African human leukocyte antigen (HLA) class I alleles, whereas a limited number of studies have identified the escape mutations on epitopes presented by Asian alleles. HLA-B54 is a common...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Disease
Share to Epitopes, T-Lymphocyte
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to HLA-B Antigens

Share to Mutation

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 19891998
DOI: 10.1016/j.humimm.2009.10.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19891998-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selection of escape mutation by Pol154-162-specific cytotoxic T cells among chronically HIV-1-infected HLA-B*5401-positive individuals.PMID 19891998Read ↗

Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes carrying strong ability to suppress HIV-1 replication.Semantic proximity Read ↗

Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.Semantic proximity Read ↗

Selection of HLA-B57-associated Gag A146P mutant by HLA-B∗48:01-restricted Gag140-147-specific CTLs in chronically HIV-1-infected Japanese.Semantic proximity Read ↗

Selection and accumulation of an HIV-1 escape mutant by three types of HIV-1-specific cytotoxic T lymphocytes recognizing wild-type and/or escape mutant epitopes.Semantic proximity Read ↗

Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele.Semantic proximity Read ↗

Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints.Semantic proximity Read ↗

Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-1.Semantic proximity Read ↗

Effect of Difference in Consensus Sequence between HIV-1 Subtype A/E and Subtype B Viruses on Elicitation of Gag-Specific CD8+ T Cells and Accumulation of HLA-Associated Escape Mutations.Semantic proximity Read ↗

Characterization of HLA-B57-restricted human immunodeficiency virus type 1 Gag- and RT-specific cytotoxic T lymphocyte responses.Semantic proximity Read ↗

Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved EpitopesSemantic proximity Read ↗

Host-specific adaptation of HIV-1 subtype B in the Japanese population.Semantic proximity Read ↗

Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.